Eastern Mediterranean Health Journal | All issues | Volume 17, 2011 | Volume 17, issue 5 | Self-medication practice among patients in a public health care system

Self-medication practice among patients in a public health care system

Print

PDF version

Research article

S.A. Alghanim1

ممارسة المداواة الذاتية لدى المرضى في ظل وجود نظام صحي عام

سعد عبد الله الغانم

الخلاصـة: تم إجراء دراسة مسحية شملت 500 من المراجعين لمراكز الرعاية الصحية الأولية بمدينة الرياض بالمملكة العربية السعودية وذلك للتعرف على مدى انتشار ظاهرة المداواة الذاتية والعوامل المرتبطة بها. أظهرت النتائج أن 35.4% من المجيبين قد قاموا بممارسة المداواة الذاتية خلال الأسبوعين السابقة لإجراء الدراسة. أشارت نتائج التحليل الثنائي والانحدار المتعدد أن فئة الشباب، والذكور، والذين أفادوا أن حالاتهم الصحية كانت متردية أو أن لديهم أمراضاً مزمنة أو صعوبة في الوصول للخدمات الصحية أو الغير راضين عن جودة الخدمة هم الأكثر ممارسة للمداواة الذاتية. إن الحملات التثقيفية، والتعليمات الصارمة المتعلقة بصرف الأدوية من الصيدليات الخاصة، وزيادة مستوى جودة الخدمة المقدمة وسهولة الوصول إليها تعتبر من التدخلات الضرورية التي يمكن أن تعمل على تعديل سلوك أفراد المجتمع ووقايتهم من الأخطار المحتملة من ممارسة المداواة الذاتية.

ABSTRACT: A survey of 500 patients attending primary health care centres in Riyadh, Saudi Arabia was carried out to determine the prevalence and factors associated with self-medication practice. The results indicated that 35.4% of the respondents had practised self-medication in the past 2 weeks. Bivariate and multivariate analyses indicated that respondents who were young, male, having poor health status, reporting inconvenient access or dissatisfied with health care were more likely to practise self-medication. Health education campaigns, strict legislations on dispensing drugs from private pharmacies and increasing the quality of and access to health care are among the important interventions that might be needed in order to change the people’s health seeking behaviour and protect them from the potential risks of self-medications.

Pratique de l’automédication chez les patients bénéficiant d’un système de soins de santé public
RÉSUMÉ:
Une enquête a été réalisée auprès de 500 patients consultant dans des centres de soins de santé primaires à Riyad (Arabie saoudite), pour déterminer la prévalence de la pratique de l’automédication et les facteurs associés. Les résultats ont indiqué que 35,4 % des répondants avaient pratiqué l’automédication au cours des deux semaines précédentes. Des analyses bivariées et multivariées ont révélé que les répondants jeunes, de sexe masculin, en mauvaise santé, trouvant l’accès aux centres de soins difficile ou leurs services non satisfaisants étaient plus susceptibles de pratiquer l’automédication. Des campagnes d’éducation sanitaire, des lois strictes sur la délivrance des médicaments par les pharmacies privées, un accès amélioré aux soins de santé et une meilleure qualité de ces derniers comptent parmi les interventions majeures qui pourraient être nécessaires pour modifier le comportement de recours aux soins et pour protéger les personnes contre les risques potentiels de l’automédication.

EMHJ, 2011, 17(5): 409-416


1Department of Public Administration, College of Business Administration, King Saud University, Riyadh, Saudi Arabia (Correspondence to S.A. Alghanim: This e-mail address is being protected from spambots. You need JavaScript enabled to view it ). Received: 29/09/09; accepted: 05/11/09

Introduction

Self-medication can be defined as the use of drugs to treat self-diagnosed disorders or symptoms, or the intermittent or continued use of a prescribed drug for chronic or recurrent disease or symptoms [1]. It may include the use of herbs, the retention and re-use of prescription drugs or the direct purchase of prescription-only drugs without medical input [2]. The practice of self-medication is common worldwide in both developed and developing countries [3,4] and may even be more common that the use of prescribed medication [5].

The importance of self-medication as a phenomenon has attracted the interest of health professionals including physicians and policy-makers, especially when drugs become deregulated and change from prescription status to be sold over-the-counter (OTC). Generally, it is accepted that self-medication has an important role in the care of minor illness [6,7]. In fact, the role of self-care was emphasized by the World Health Organization (WHO) in 1978 in its “Health for all by year 2000” initiative, which was implemented in many countries of the world including Saudi Arabia. Many possible benefits [8,9] and risks [10,11] have been attributed to increased self-medication among the public. Studies indicated that the use of self-medication is influenced by several personal [12], organizational [13] and environmental factors [14]. The failure of a health care system, when there is maldistribution of health resources and a resultant growth in health care costs, has been mentioned as a factor in self-medication [15].

In Saudi Arabia, private sector pharmacies are the most accessible health facilities and people can obtain most types of medication without a prescription, which makes self-medication easy to practice. Despite some studies conducted on this topic [16–18], self-medication has not received the attention it deserves as a research topic. The majority of studies on self-medication were conducted in countries where the health care system and culture are different from that of Saudi Arabia. Accordingly, the results may not be transferable to the Saudi context. Data on the prevalence of, and factors associated with, self-medication in Saudi Arabia are necessary to help with the planning of interventions to improve the self-use of medicines in the country.

This study aimed to determine the prevalence of self-medication among Saudi adult patients; to identify potential factors that could influence self-medication practices; to identify sources of medications used; to identify sources of information about medications used; and to identify reasons for self-medication.

Methods

Sample

This was a community-based, cross-sectional survey carried out in Riyadh city, the capital of Saudi Arabia, to explore self-medication behaviour among the general population. The study population consisted of all patients attending primary health care (PHC) centres in Riyadh city during July 2009. Five PHC centres were selected using cluster random sampling in order to represent the 5 geographical areas of Riyadh city (north, east, south, west and centre). In each PHC centre, a sample of 100 adult patients (18–65 years) was selected using systematic random sampling. Accordingly, 500 questionnaires were completed and returned, a response rate of 100%.

Data collection

The study questionnaire consisted of 5 sections, including both open- and closed-ended questions. The first section included questions on sociodemographic characteristics, including sex, age, nationality, educational level and employment status. The second section was used to collect information on self-reported health aspects of respondents, such as their perception about their health status, whether they had any chronic illness, their perception about access to health care and their satisfaction with the health care they usually receive. Respondents were also asked whether they had practised self-medication during the 2 weeks preceding the survey. In the third and fourth sections, respondents were requested to report on the sources of medication used for self-treatment and sources of information about such medication. The final section contained questions about respondents’ reasons for self-medication.

In order to increase the content validity of the questionnaire, a number of steps were carried out. First, a review of the relevant literature was conducted. Second, 2 academic staff reviewed the draft questionnaire. Finally, a pilot survey of 50 adult patients (27 males and 23 females) was conducted in 2 PHC centres in Riyadh city. On the basis of the suggestions of the reviewers and the outcome of the pilot survey, a few questions were reformulated and others were added or deleted in the main study. The pilot survey questionnaires were not included in the main survey.

The respondents were assured of confidentiality and provided with an explanation about the purpose of the study and the importance of their contribution. The subjects gave verbal consent to participate in the study. All questionnaires were distributed and collected by 10 research students (5 males and 5 females). Students were given an intensive training course on data collection and management of the survey. All questionnaires were completed during the respondents’ waiting time in the selected primary health care centres. Questionnaires were completed in the presence of the research students in case some participants required assistance.

In this study, self-medication was defined as the use of modern drugs without the advice of a health professional [17].

Data analysis

The outcome of the study was the practice of self-medication in the past 2 weeks. Respondents were classified into 2 groups: those who practised self-medication and those who did not (yes/no). The chi-squared test was used to determine the differences between these 2 groups according to demographic-related characteristics, which included respondents’ sex, age, educational level, marital status and employment status; and health-related aspects which included respondents’ self-reported health status, whether they had a chronic illness, perceptions about access to health care and satisfaction with the quality of health care they receive. A logistic regression analysis was performed to identity factors that were significantly associated with self-medication. The multivariate-adjusted odds ratios (OR) and the corresponding 95% confidence intervals (CI) were calculated. All tests were 2-tailed with a statistical significance level of 0.05. The data for this study were entered and analysed using the SPSS, version 11.0.

Results

Background characteristics

A total of 500 adult patients were surveyed. They were predominantly young with a mean age of 38.6 (SD 12.9) years (range 18–65 years). Of these, 279 (55.8%) were males and 221 (44.2%) were females. The great majority of respondents were of Saudi Arabian nationality (82.4%), married (65.8%), had an educational level of high school or above (53.8%) and were in employment (73.4%).

Self-medication practices

Respondents who had practised some sort of self-medication during the past 2 weeks were 177 (35.4%) of the sample. The sources of medicine used by these patients are shown in Table 1. OTC drugs purchased from private pharmacies was the most commonly used source of self-medication, reported by the majority of self-medicated patients (79.1%). The use of left-over medicine was also prevalent and reported by almost half of respondents who practised self-medication (48.6%). Those who obtained medications from their relatives, friends or neighbours constituted nearly one-third of self-medicated respondents (30.5%).

Patients who practised self-medication in the past 2 weeks were asked about the source of information about the drugs they used for self-medication. Table 1 shows that the commonest source of information was the private sector pharmacy salesmen (including pharmacists), reported by about three-quarters of respondents (74.0%). This was followed by respondents’ experiences or knowledge from previous episodes (50.8%). Health staff was the least common source of information, reported by only 9.6% of respondents. Other sources of information about medications were relatives/friends, the Internet and advertisements.

The study identified patients’ reasons for self-medication (Table 1). The commonest was that the illness was regarded as minor (80.2%). More than two-thirds of respondents (70.1%) indicated that they self-medicated because health care facilities were unavailable at times when they needed care. More than half of self-medicated respondents (52.0%) reported that they did so because they lacked the time to visit formal health care facilities. More than 40% of self-medicated patients indicated that the cost of consultations with the doctor was a reason for self-medication. Other reasons for self-medication were expectations of less/no benefit from modern health care, remoteness of health care sites and convenience.

Table 1 Sources of medications and information on self-medication and reasons for using self-medication in the past 2 weeks (n = 177)

Characteristics of patients who used self-medication

Table 2 shows the descriptive association between sociodemographic characteristics and self-medication behaviour in the past 2 weeks. The results indicate that males were a significantly higher percentage of self-medicaters than females (44.8% versus 23.5%) (P < 0.001). Similarly, more of the younger respondents and those with a higher level of education were using self-medication than their counterparts (P < 0.05). A significantly higher rate of self-medication was reported by respondents who perceived their health status as poor versus good (47.4% versus 28.1%) (P < 0.001), those having chronic illness versus those who did not (45.5% versus 31.4%) (P < 0.05), those who reported inconvenient access to health care facilities versus those with convenient access (46.3% versus 30.1%) (P < 0.05) and those who were dissatisfied with the quality of their health care versus those who were satisfied (46.5% versus 32.1%) (P < 0.05).

Table 2 Demographic profile and health status according to use of self-medication in the past 2 weeks by respondents

Regression analysis

Table 3 provides the adjusted OR and 95% CI that quantify the association between the independent variables (sociodemographic factors and health-related factors) and the outcome variable (self-medication practice in the past 2 weeks). These estimates were obtained using the logistic regression analysis. Among the sociodemographic variables, age and sex were statistically associated with self-medication. Younger respondents were about twice more likely to practise self-medication than older ones (OR = 2.19, 95% CI: 1.35–3.56) (P < 0.05). Similarly, males were 3.5 times more likely to practise self-medication than females (OR = 3.56, 95% CI: 2.15–5.89) (P < 0.001). All heath-related factors employed in the study were found to be statistically associated with self-medication. In particular, respondents who perceived their health status as poor were about 2.5 times more likely to practise self-medication than those who perceived their health status as good (OR = 2.57, 95% CI: 1.66–3.99) (P < 0.001). Respondents who reported having chronic conditions were 1.6 times more likely to self-medicate than those who did not (OR = 1.64, 95% CI: 1.03–2.62) (P < 0.05). Similarly, respondents who perceived their access to health care as inconvenient were about twice as likely to self-medicate than those who reported convenient access (OR = 2.07, 95% CI: 1.34–3.18) (P < 0.05). The results also show that respondents who were dissatisfied with the quality of health care they received from health care facilities were more than 3 times likely to practise self-medication than those who were satisfied (OR = 3.13, 95% CI: 1.82–5.40) (P < 0.001).

Table 3 Characteristics associated with use of self-medication in the past 2 weeks  

Discussion  

Over a period of 2 weeks before this survey, 35.4% of respondents had used self-medication alone or in combination with a prescrition medication. This finding is surprising since most of the population in Saudi Arabia are eligible for free public health services. However, this prevalence supports the findings reported earlier by other studies conducted in Saudi Arabia [16–18] and confirms the notion that self-medication is widespread among the general population. Recent studies conducted in different parts of the world such as the United States [19], the United Kingdom [20], Spain [21], Germany [22], France [23], Mexico [24], Singapore [25], Turkey [26], Pakistan [27], Jordan [28], Kuwait [29], Egypt [30] and Sudan [2] vary in their estimation of the percentage of patients who practise self-medication, with prevalence rates that range from about 13% to 92%. Comparing the results of the present study with those in the literature is difficult since studies differ in their definitions of self-medication and in the methodologies employed and many countries also differ in their cultures, health care systems and the perceived role of pharmacists. However, there is a general agreement among these studies that self-medication has potential risks and that despite efforts exercised by health care professionals and decision-makers to limit this problem, rates of self-medication are on the rise.

The data from the present study indicated that 2 of the sociodemographic variables (age and sex) and 4 health-related variables (perceived health status, presence of chronic illness, perceived access to health care and satisfaction with health care) had a significant independent association with the practice of self-medication. Young individuals were more likely to administer self-medication than older ones. This finding is consistent with other studies [31]. However, the results of the present study indicated that men were more inclined to self-medication than women, which contradicts results reported by other studies in the literature [32]. These findings are expected given the fact that young males are more mobile than older people or women. Women in Saudi Arabia are not permitted to drive a car and many do not leave home without a male escort; accordingly they are less likely to seek medicine from sources such as private pharmacies in the community. Despite the fact that the respondents’ level of education was a significant factor in the bivariate analysis, it did not enter the logistic regression model as a significant predictor of self-medication practice. This finding contradicts previous research conducted in Saudi Arabia [16] and elsewhere [2], which reported that the level of education of patients has an impact on the practice of self-medication.

The results of this study showed that respondents with negative self-reported health status, those who reported having chronic illness and those who had difficulties in accessing health care facilities were more likely to practise self-medication than those who did not report such perceptions or health conditions. This finding agrees with other studies in the medical literature [4,24]. It is worth noting that numerous authors have studied the relationship between self-medication and factors related to patients’ sociodemographic and health-related characteristics. The majority of these studies showed that self-medication was mainly associated with health needs or health-related variables, such as self-reported health status, presence of chronic diseases and severity of symptoms. Other authors reported that patients who have poor health or have difficulty in accessing health care are more likely to use self-medication and become frequent users of OTC drugs in an attempt to resolve their health problems [33].

In keeping with the findings of other authors [34], satisfaction with the quality of health services is an important determinant of health resource utilization. In the present study patients who were dissatisfied with the quality of health services provided to them in health care facilities such as primary health care centres were more likely to practise self-medication. An individual’s decision to use a particular source of health care involves many factors related to sociodemographic characteristics, illness type and severity, perceived health status and the range and accessibility of therapeutic options available and their perceived efficacy [35,36].

The data from the present study indicated that about 80% of respondents who reported using self-medication identified that the private pharmacy was a major source of both medicine and information. This is not surprising since it is possible for any individual in Saudi Arabia to buy any drug products OTC without any prescription, except for a very limited number of drugs which may require a special prescription for dispensing. This finding is consistent with previous work reported from other neighbouring countries such as Egypt [30], Palestine [12], Sudan [9] and Jordan [8], which indicate that community pharmacies in these countries play a major role in the wide prevalence of self-medication among the population. This is probably due to the weak enforcement of regulations regarding drug handling and dispensing. Consequently, salesmen of community pharmacies are commonly considered as a major source of medicine without prescriptions.

The results of this study indicated that health staff were the least influential source of information about self-medication. This is to be expected, since many people have the impression that doctors do not approve of self-medication [5]. It is well-known that many doctors are reluctant to advise patients on self-medication or issue medicine without a clinical examination. However, in terms of patients’ general sources of knowledge about health care matters, studies show the importance of the mass media in increasing people’s knowledge about health care issues and that such sources provide more information than patients receive from health care settings. This may provoke questions about the health education programmes that are implemented in health care facilities and the doctor–patient relationship.

In this study, respondents identified several reasons for self-medication, including that their illness was minor, no medical services were available, lack of time to attend health facilities, waiting times to be seen and the cost of consultations. While such reasons were similar to those reported in previous research [4,9,21], they raise a number of questions relevant to the Saudi context. For example, are patients well-informed on what constitutes minor illness? Are the working hours of the primary health care facilities suitable? Are the waiting times acceptable? How do patients perceive the quality of health services provided to them? These questions, which are mainly related to the availability of, and accessibility to, health care services, need to be answered in further research.

Several limitations should be considered when interpreting the results of the present study. First, the study was limited to self-medication. Nevertheless, the findings have implications for drugs sold OTC and the dissemination of information about drugs and their potential side-effects. Secondly, respondents were asked to report on self-medication over a period of 2 weeks only. This may have influenced the results of the study. However, reporting on self-medication over a period of 2 weeks has been used in recent studies conducted in different parts of the world [21,37,38] in order to limit recall bias and to avoid problems associated with recall and reporting of health care events. Thirdly, due to time and financial constraints, the present study was limited to Riyadh city. However, Riyadh is the largest city in Saudi Arabia, with many inhabitants with different sociodemographic characteristics. Finally, the results reported here were based on self-reported information and are therefore subjective. Despite these limitations, the study may stimulate more attention to, and research into, the prevalence, effectiveness and side-effects of self-medication in Saudi Arabia.

This study revealed a considerable rate of self-medication in the Saudi population, which should draw the attention of policy-makers to this problem. The findings of this study will encourage greater exploration of the role of self-medication in health care. Health policies should focus on ensuring that people have adequate access to health care and that the population is given information about the hazards posed by self-medication.

Acknowledgements

The author would like to thank the Research Centre, College of Business Administration at King Saud University for financing this study.

References

  1. Guidelines for the regulatory assessment of medicinal products for use in self-medication. Geneva, World Health Organization, 2000 (WHO/EDM/QSM/00.1).
  2. Awad A et al. Self-medication with antibiotics and antimalarials in the community of Khartoum State, Sudan. Journal of Pharmacy and Pharmaceutical Sciences, 2005, 8:326–331.
  3. Figueiras A, Caamaño F, Gestal-Otero JJ. Sociodemographic factors related to self-medication in Spain. European Journal of Epidemiology, 2000, 16:19–26..
  4. Fuentes Albarrán K, Villa Zapata L. Analysis and quantification of self-medication patterns of customers in community pharmacies in southern Chile. Pharmacy World and Science, 2008, 30:863–868.
  5. Lam CL, Tse MH, Munro C. A survey on the use of self medication over a period of two Weeks. Hong Kong Practitioner, 1989, 11:371–375.
  6. Guidelines for the medical assessment of drugs for use in self-medication. Copenhagen, World Health Organization Regional Office for Europe, 1986.
  7. Hayran O, Karavus M, Aksayan S. Help-seeking behavior and self-medication of a population in an urban area in Turkey: cross sectional study. Croatian Medical Journal, 2000, 41:327–332.
  8. Yousef AM et al. Self-medication patterns in Amman, Jordan. Pharmacy World and Science, 2008, 30:24–30.
  9. Awad AI, Eltayeb IB, Capps PA. Self-medication practices in Khartoum State, Sudan. European Journal of Clinical Pharmacology, 2006, 62:317–324.
  10. Hamel MJ et al. Malaria control in Bungoma District, Kenya: a survey of home treatment of children with fever, bednet use and attendance at antenatal clinics. Bulletin of the World Health Organization, 2001, 79:1014–1023.
  11. Promoting rational use of medicines: core components. WHO policy perspectives on medicines. Geneva, World Health Organization, 2002 (WHO/EDM/2002.3).
  12. Sawalha AF. A descriptive study of self-medication practices among Palestinian medical and nonmedical university students. Research in Social and Administrative Pharmacy, 2008, 4:164–172.
  13. De Boer MJ, Versteegen GJ, van Wijhe M. Patients’ use of the Internet for pain-related medical information. Patient Education and Counseling, 2007, 68:86–97.
  14. Worku S. G/Mariam A. Practice of self-medication in Jimma town. Ethiopian Journal of Health Development, 2003, 17:111–116.
  15. Heisler M et al. The health effects of restricting prescription medication use because of cost. Medical Care, 2004, 42:626–634.
  16. Saeed AA. Self-medication among primary care patients in Farazdak Clinic in Riyadh. Social Science & Medicine, 1988, 27:287–289.
  17. Azab AS. Public knowledge, attitude and practice towards antibiotics use in Riyadh city. Saudi Medical Journal, 2000, 21:784–785.
  18. Abahussain NA, Taha AZ. Knowledge and attitudes of female school students on medications in eastern Saudi Arabia. Saudi Medical Journal, 2007, 28:1723–1727.
  19. Bent S. Herbal medicine in the United States: review of efficacy, safety, and regulation: grand rounds at University of California, San Francisco Medical Center. Journal of General Internal Medicine, 2008, 23:854–859.
  20. Oborne CA, Luzac ML. Over-the-counter medicine use prior to and during hospitalization. Annals of Pharmacotherapy, 2005, 39:268–273.
  21. Carrasco-Garrido P et al. Predictive factors of self-medicated drug use among the Spanish adult population. Pharmacoepidemiology and Drug Safety, 2008, 17:193–199.
  22. Uehleke B, Steinhoff B. Self-medication in Germany. International Journal of Clinical Pharmacology and Therapeutics, 2001, 39:484–487.
  23. Orriols L et al. Evaluation of abuse and dependence on drugs used for self-medication: a pharmacoepidemiological pilot study based on community pharmacies in France. Drug Safety, 2009, 32:859–873.
  24. Balbuena FR, Aranda AB, Figueras A. Self-medication in older urban mexicans : an observational, descriptive, cross-sectional study. Drugs and Aging, 2009, 26:51–60.
  25. Chui WK, Li SC. Advice-giving on self-medication: perspectives of community pharmacists and consumers in Singapore. Journal of Clinical Pharmacy and Therapeutics, 2005, 30:225–231.
  26. Gül H et al. Nonprescription medication purchases and the role of pharmacists as healthcare workers in self-medication in Istanbul. Medical Science Monitor, 2007, 13:PH9–PH14.
  27. Zafar SN et al. Self-medication amongst university students of Karachi: prevalence, knowledge and attitudes. Journal of the Pakistan Medical Association, 2008, 58:214–217.
  28. Sawair FA et al. Assessment of self-medication of antibiotics in a Jordanian population. Medical Principles and Practice, 2009, 18:21–25.
  29. Awad A, Al-Rabiy S, Abahussain E. Self-medication practices among diabetic patients in Kuwait. Medical Principles and Practice, 2008, 17:315–320.
  30. Sallam SA et al. Pharmacoepidemiological study of self-medication in adults attending pharmacies in Alexandria, Egypt. Eastern Mediterranean Health Journal, 2009, 15:683–691.
  31. Linden M et al. Self medication with St. John’s wort in depressive disorders: an observational study in community pharmacies. Journal of Affective Disorders, 2008, 107:205–210.
  32. Carrasco-Garrido P et al. Patterns of medication use in the immigrant population resident in Spain: associated factors. Pharmacoepidemiology and Drug Safety, 2009, 18:743–750.
  33. Stasio MJ et al. Over-the-counter medication and herbal or dietary supplement use in college: dose frequency and relationship to self-reported distress. Journal of American College Health, 2008, 56:535–547.
  34. Zineldin M. The quality of health care and patient satisfaction: An exploratory investigation of the 5Qs model at some Egyptian and Jordanian medical clinics. International Journal of Health Care Quality Assurance, 2006, 19:60–92.
  35. Fernandez-Olano C et al. Factors associated with health care utilization by the elderly in a public health care system. Health Policy, 2006, 75:131–139.
  36. Ahmed SM et al. Gender, socioeconomic development and health-seeking behaviour in Bangladesh. Social Science and Medicine, 2000, 51:361–371.
  37. Suleman S, Ketsela A, Mekonnen Z. Assessment of self-medication practices in Assendabo town, Jimma zone, southwestern Ethiopia. Research in Social and Administrative Pharmacy, 2009, 5:76–81.
  38. Leyva-Flores R, Kageyama ML, Erviti-Erice J. How people respond to illness in Mexico: Self-care or medical care? Health Policy,  2001, 57:15–26.