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Trachoma elimination: Iranians triumph against the world’s leading infectious cause of blindness

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26 September 2018 | Tehran | Cairo | Geneva - The World Health Organization (WHO) has validated the elimination of trachoma as a public health problem in the Islamic Republic of Iran. By achieving this milestone, the country becomes the third in WHO’s Eastern Mediterranean Region, after Oman in 2012 and Morocco in 2016, to overcome this centuries-old disease.

“WHO is pleased to have supported the Islamic Republic of Iran through the validation process,” said Dr Ahmed Al-Mandhari, WHO Regional Director for the Eastern Mediterranean. “But this achievement was made possible by the Government and people of Islamic Republic of Iran, who have worked tirelessly over decades to eliminate trachoma as a cause of preventable blindness and unnecessary suffering.”

The long fight

Trachoma was a major cause of visual impairment in Islamic Republic of Iran in the early decades of the 20th century.

In 1959, in rural areas of the district of Malayer, two thirds of the population were affected by the disease. A survey in the Dezful district in 1961 showed that 91% of people were affected, including 62% with the active (inflammatory) form. At that time, prevalence in the capital, Tehran, was estimated to be 30–40%.

In 1972, tetracycline ointment was introduced as an essential medication in the Health facilities of Iran, and was provided free of charge to people who needed it for treatment of active trachoma.

Ophthalmologists were trained during their residency programmes to perform surgical management of trichiasis: the advanced, sight-threatening form of trachoma. Health education campaigns designed jointly by the Ministry of Health and Medical Education and the Ministry of Education, including messages about washing hands and faces, were delivered as part of broad-based hygiene improvement initiatives in preschools and primary schools.

“In 2003, as part of the drive to accelerate elimination and with self-health care as one of its components, we introduced an awareness-raising programme in more than 20 000 schools in regions and localities endemic for the disease,” said Dr Hassan Ghazizadeh Hashemi, HE Minister of Health and Medical Education of Islamic Republic of Iran. Dr Seyed-Farzad Mohammadi, National Coordinator for Eye Health, Prevention of Blindness and Trachoma Control. ”This benefited entire regions by improving the health of students, school personnel, parents and communities.”

In parallel, the Steering Committee for the National Water Programme – a joint committee of the Ministry of Energy and the Environmental Health Centre of the Ministry of Health and Medical Education – allocated US $500 million to improve water supply and sewerage systems in remote areas.

Edging towards success

In 2004, assessments were undertaken in rural areas of four provinces (Bushehr, Kerman, Hormozgan, and Sistan and Baluchestan) in the south of Islamic Republic of Iran, where trachoma was last recognized as a problem. These surveys showed nearly a complete absence of disease. Active trachoma was only seen in Sistan and Baluchestan, where less than 1% of children were affected by the disease.

In 2012–2013, a population-based prevalence study in rural areas of Sistan and Baluchestan re-estimated the prevalence of trachoma at 0.6% of children.

“We expected to see a very low prevalence of trachoma,” said Dr Seyed-Farzad Mohammadi, National Coordinator for Eye Health, Prevention of Blindness and Trachoma Control. “We knew that trachoma transmission had decreased. We’re sure that this in part is due to better access to water and sanitation: 2015 UNICEF/WHO Joint Monitoring Programme data estimated that 92% of households in rural areas had access to improved drinking-water and nearly 100% had access to improved sanitation.”

Appropriate plans were put in place to ensure ongoing provision of services to individuals who might develop complications of trachoma later in life. All criteria for validation of elimination of trachoma as a public health problem[1] have been met.

Trachoma disease

Trachoma, a devastating eye disease caused by infection with the bacterium Chlamydia trachomatis, is spread through contact with infective eye or nose discharges, either directly from person to person, or mediated by flies. Active (inflammatory) trachoma occurs as a result of infection, and is common among preschool-aged children. Women are blinded up to four times as often as men, mainly due to their close contact with infected children.

Transmission is associated with poor sanitation and hygiene, which increase eye discharges and encourage the breeding of flies.

GET2020

In 1996, WHO launched the WHO Alliance for the Global Elimination of Trachoma by the year 2020 (GET2020). With other partners in the Alliance, WHO supports country implementation of the SAFE strategy and strengthening of national capacity through epidemiological assessment, monitoring, surveillance, project evaluation and resource mobilization.

Interventions to eliminate trachoma are inexpensive, simple and extremely cost effective, yielding a high rate of net economic return.

For more information:

Dr Christoph Hamelmann
WHO Representative to the Islamic Republic of Iran
Tel:  +98 21 88363979-80 (Ext: 61222)
Email: This e-mail address is being protected from spambots. You need JavaScript enabled to view it

Mr Ashok Moloo
Information Officer
Neglected Tropical Diseases, WHO/HQ
Tel: +41 22 791 1637
Email: This e-mail address is being protected from spambots. You need JavaScript enabled to view it


[1] WHO has now validated elimination of trachoma as a public health problem in the following countries:  Cambodia, Ghana, Islamic Republic of Iran, Lao People's Democratic Republic, Mexico, Morocco, Nepal and Oman.