World AIDS Day 2025

Overcoming Disruption, Transforming the AIDS Response

1 December 2025

The Eastern Mediterranean Region is facing a fast growing HIV epidemic, with an estimated 620 000+ people living with HIV (PLHIV). Only 38% have been diagnosed, and just 28% are receiving treatment, leaving 2 out of 3 people unaware of their status.

In recent years, reductions in global funding have disrupted HIV prevention, testing and treatment services across the Region, threatening progress and placing additional pressure on national health systems already stretched by multiple crises.

Under the global theme Overcoming Disruption, Transforming the AIDS Response, this year’s World AIDS Day campaign calls on countries, communities and partners to reignite commitment, embrace innovation, integrate HIV services into broader health programmes, act against stigma and structural barriers to treatment and scale up the response towards HIV in the Region.

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Key messages and call to action

The World AIDS Day 2025 campaign seeks to engage government leaders, national HIV programmes, partners, community-based organizations and stakeholders. It calls for:

Sustained political commitment to keep HIV high on national health agendas
Increased national investments
The integration of HIV services into broader health programmes to deliver comprehensive, people-centred care
Innovations in service delivery, including through HIV self-testing, community-based approaches and differentiated care models
Strengthened prevention through PrEP expansion, harm reduction and active community engagement
Improvements in data generation and use, with a focus on digital/AI innovations to enhance surveillance, monitoring and targeted HIV responses