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  1. Genetic diseases

Genetic diseases

Globally, it is estimated that about 7.9 million births or 6% of total births annually occur with a defect of genetic or partially genetic origin. With a high prevalence of genetic disorders such as haemoglobinopathies (thalassemias and sickle cell), countries in the Eastern Mediterranean Region share a large part of this burden accounting for as much as 26% of the annual total conceptions with β-thalassemia worldwide. Carrier rates, as high as 50% for α-thalassemia and 30% for sickle cell are observed in some countries of the Region or within specific populations within these countries. Cultural practices, such as consanguineous marriages, are important contributors to this high prevalence.

The World Health Assembly has adopted two resolutions on hemoglobin disorders: resolution WHA59.20 on sickle-cell anemia, adopted by the Fifty-ninth World Health Assembly in May 2006; and resolution WHA63.17 on birth defects, including sickle-cell disease and thalassemia, adopted by the Sixty-third World Health Assembly in May 2010.

Information resources

Policy documents

Resolution WHA63.17 on birth defects, including sickle-cell disease and thalassemia

Executive Board Resolution on Thalassaemia

Plan of action for the prevention and control of noncommunicable diseases in the Eastern Mediterranean Region

Prevention and control of noncommunicable diseases: report of the Secretary-General

A prioritized research agenda for prevention and control of noncommunicable diseases, 2011

Package of essential noncommunicable (‎PEN)‎ disease interventions for primary health care in low-resource settings

 

Links

Thalassaemia International Federation

European Genetics Foundatiom

Centers for Disease Control and Prevention (CDC), Atlanta

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The National Center for Diabetes, Endocrinology & Genetics Diseases, Jordan (WHO CC for Diabetes Research, Education and Primary Health Care)

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